Discovery of New Bat Coronavirus HKU5-CoV-2 Raises Public Health Concerns
Researchers have discovered a new bat coronavirus named HKU5-CoV-2 in China, which could infect humans like SARS-CoV-2. The virus binds to human ACE2 cells, similar to the COVID-19 virus, but current studies suggest that the risk of a new pandemic is minimal due to population immunity and lower viral binding affinity.
A newly identified bat coronavirus, HKU5-CoV-2, poses potential risks for animal-to-human transmission akin to the virus responsible for the COVID-19 pandemic. Research conducted by a team led by renowned virologist Shi Zhengli at the Wuhan Institute reveals that HKU5-CoV-2 shares similarities with SARS-CoV-2, particularly in its ability to interact with human ACE2 cells, which allow for viral entry.
Classified under the merbecovirus subgenus, HKU5-CoV-2 has shown the ability to infect human cell cultures during laboratory testing. It has been observed to bind to human ACE2 receptors similarly to SARS-CoV-2. The study notes that bat merbecoviruses pose a significant risk for potential spillover to humans through direct contact or via intermediate hosts, although further research is required to fully understand this risk.
Dr. Michael Osterholm, an expert in infectious diseases, has addressed fears regarding the possibility of a new pandemic stemming from HKU5-CoV-2. He referenced the robust immunity present in today’s population against similar coronaviruses, suggesting it could mitigate the pandemic threat. The study clarifies that HKU5-CoV-2 demonstrates lower binding affinity to humanACE2 compared to SARS-CoV-2, and various factors indicate that the likelihood of emergence in humans is reduced.
The discovery of the HKU5-CoV-2 virus raises important questions regarding potential zoonotic risks; however, the current scientific consensus indicates a low risk of a future pandemic. The presence of existing immunity against coronaviruses within the population may further diminish concerns surrounding this new virus. Continued research is essential to monitor and assess the potential impact of HKU5-CoV-2 on human health.
Original Source: www.ndtv.com
